ʻO Ivermectin

Hōʻike Pōkole:

Helu CAS :70288-86-7

Molecular haʻilula: C48H74O14


ʻIke kikoʻī

Nā huahana huahana

ʻO Ivermectin

ʻO Ivermectin he keʻokeʻo crystalline keʻokeʻo, ʻaʻohe onaona. ʻAe maʻalahi ia i ka methanol, ethanol, acetone, ethyl acetate, hiki ʻole ke waiho ʻia i loko o ka wai, a me kahi hygroscopic. ʻO Ivermectin kahi antibiotic macrolide semisynthetic macrolide nunui, kahi i loko o ivermectin B1 (Bla + B1b) ʻike ma lalo o 93%, a ʻo Bla ka ʻike ma lalo o 85%.

ivermectin-drum

Kumuhana o ka Lapaʻau

Loaʻa i kēia huahana kahi hopena inhibitory koho, ma o ka hoʻopaʻa ʻana i ka nui o nā kahawai koloride me ka glutamate e like me ka kiwikā i nā hunaola a me nā hunaola o nā holoholona spinless, kahi e alakaʻi ai i ka hoʻonui ʻana o ka permeability o nā membrane pūnaewele i nā iona chloride, ke kumu o ka hyperpolarization o ke aʻalolo. nā hunaola a i ʻole nā ​​ʻili mākala, a kumu i ka maʻi lōlō a i ʻole ka make ʻana o nā parasites. Hoʻopili pū kekahi me nā kahawai koloride o nā valves ligand ʻē aʻe, e like me ka neurotransmitter g-aminobutyric acid (GABA). ʻO ke koho ʻana o kēia huahana no ka loaʻa ʻole o nā kahawai glutamate-chloride i kekahi mau mamamals ma vivo, a he haʻahaʻa haʻahaʻa wale nō ka avermectin no nā kahawai ligand-chloride mammalian. ʻAʻole hiki i kēia huahana ke komo i loko o ka pale o ka lolo-kanaka. ʻO Onchocerciasis a me strongyloidiasis a me hookworm, ascaris, Trichuris trichiura, a me Enterobius vermicularis maʻi.

Ke hoʻohana nei

ʻO Ivermectin kahi lāʻau i hoʻohana ʻia e mālama i nā ʻano ʻino o ka parasite infestations. Hoʻohana ʻia ʻo Ivermectin e mālama i nā maʻi o nā holoholona i hoʻokumu ʻia e nā roundworms a me nā ectoparasites.

Hoʻohana mau ʻia ʻo Ivermectin e kaohi i nā ilo worm i ka gastrointestinal tract o nā holoholona ruminant. Komo mau kēia mau parasites i ka holoholona ke hānai ia, hele i ka ʻōpū, a hoʻonohonoho a oʻo i loko o nā ʻōpū, a laila hana lākou i nā hua manu e waiho i ka holoholona ma o ka wai lepo a hiki ke hoʻopiha i nā wahi hou. He kūpono ʻo Ivermectin i ka luku ʻana i kekahi, akā ʻaʻole naʻe, o kēia mau parasite. I nā ʻīlio e hoʻohana mau ʻia ia ma ke ʻano he prophylaxis e kūʻē i ka puʻuwai.

I nā lāʻau lapaʻau lāʻau, hoʻohana ʻia ia e pale a mālama i ka heartworm a me ka acariasis, i waena o nā hōʻailona ʻē aʻe. Hiki ke lawe ʻia e ka waha a i ʻole hoʻopili ʻia i ka ʻili no nā infestations kūwaho. Hoʻohana nui ʻia ʻo Ivermectin no ka nematodes gastrointestinal, lungworms, a me nā parasropods i loko o nā bipi, nā hipa, nā lio, a me nā puaʻa, nā nematode ʻōpū i nā ʻīlio, nā pepeiao pepeiao, nā Sarcoptes scabiei, nā puʻuwai filariae, a me nā microfilariae, a me nā nematodes gastrointestinal a me nā ectoparasites i nā manu.

Nā hoʻomākaukau

Ivermectin injection1%, 2%, 3.4%, 4%;
Ivermectin haʻina waha 0.08%, 0.8%, 0.2%;
Ivermectin premix;

Ivermectin bolus;
Ivermectin ninini hoʻonā i 0.5%, 1%;
Ivermectin gel 0.4%


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